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DMPK Editors' Award for the Most Excellent Article in 2017
- 【1st Place】
Quantitative prediction of therapeutic antibody pharmacokinetics after intravenous and subcutaneous injection in human
Kenta Haraya, Tatsuhiko Tachibana, Junichi Nezu
Volume 32, Issue 4, 2017, Pages 208-217
https://doi.org/10.1016/j.dmpk.2017.05.002
- 【2nd Place】
Development of Caco-2 cells co-expressing CYP3A4 and NADPH-cytochrome P450 reductase using a human artificial chromosome for the prediction of intestinal extraction ratio of CYP3A4 substrates
Toru Takenaka, Kanako Kazuki, Naomoto Harada, Jiro Kuze, Masato Chiba, Takahiro Iwao, Tamihide Matsunaga, Satoshi Abe, Mitsuo Oshimura, Yasuhiro Kazuki
Volume 32, Issue 1, 2017, Pages 61-68
https://doi.org/10.1016/j.dmpk.2016.08.004
- 【3rd Place】
Quantitative prediction of histamine H1 receptor occupancy by the sedative and non-sedative antagonists in the human central nervous system based on systemic exposure and preclinical data
Kayoko Kanamitsu, Yoshitane Nozaki, Yoko Nagaya, Yuichi Sugiyama, Hiroyuki Kusuhara
Volume 32, Issue 2, 2017, Pages 135-144
https://doi.org/10.1016/j.dmpk.2016.11.007
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DMPK Editors' Award for the Most Excellent Article in 2016
- 【1st Place】
Prediction of CNS occupancy of dopamine D2 receptor based on systemic exposure and in vitro experiments
Kanamitsu K., Arakawa R., Sugiyama Y., Suhara T., Kusuhara H.
Vol. 31 (2016) No. 6 p. 395-404
http://www.sciencedirect.com/science/article/pii/S1347436716300441
- 【2nd Place】
Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for
interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(−/−) rats
Nagaya Y., Nozaki Y., Takenaka O., Watari R., Kusano K., Yoshimura T., Kusuhara H.
Vol. 31 (2016) No. 1 p. 57-66
http://www.sciencedirect.com/science/article/pii/S1347436715000622
- 【3rd Place】
Inhibition of mitogen-activated protein kinase kinase, DNA methyltransferase, and
transforming growth factor-β promotes differentiation of human induced pluripotent stem cells into
enterocytes
Kodama N., Iwao T., Kabeya T., Horikawa T., Niwa T., Kondo Y., Nakamura K., Matsunaga T.
Vol. 31 (2016) No. 3 p. 193-200
http://www.sciencedirect.com/science/article/pii/S134743671600015X
- 【3rd Place】
Development of a permeability-limited model of the human brain and cerebrospinal fluid(CSF) to integrate known physiological and biological knowledge: Estimating time varying CSF drug concentrations and their variability using in vitro data
Gaohua L., Neuhoff S., Johnson T.N., Rostami-Hodjegan A., Jamei M.
Vol. 31 (2016) No. 3 p. 224-233
http://www.sciencedirect.com/science/article/pii/S1347436716300088
- 【3rd Place】
Appropriate risk criteria for OATP inhibition at the drug discovery stage based on the
clinical relevancy between OATP inhibitors and drug-induced adverse effect
Nakakariya M., Goto A., Amano N.
Vol. 31 (2016) No. 5 p. 333-339
http://www.sciencedirect.com/science/article/pii/S1347436716300234
... Go DMPK (Vo.17, 2002〜current issue)
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