Newsletter Volume 41, Number 1, 2026

DMPK 66に掲載予定の論文一覧

[Review]

Review article

Positive implications of PBPK platform qualification for predicting drug–drug interactions: Taking on cracks only to see bigger gaps!

Amin Rostami-Hodjegan

 

Review article

Evaluation of OATP1B inhibitory potential using an endogenous biomarker coproporphyrin-I in new drug applications: Case reports submitted by 2024

Ryosuke Watari

 

Review article

Current status of prediction of IL-6 mediated cytochrome P450 activity modulation using in vitro data and PBPK modeling

Viktor Georgiev, Isabelle Anderka, Delia Bucher, Lena Preiss, … Neil Parrott

 

Review article

Future directions in drug-drug interaction evaluations: Industry perspective on the ICH M12 guidance

Kenichi Umehara, Andrew Harrell, Chandra Prakash, Constanze Hilgendorf, … Yuan Chen

 

Review article

Cytochrome P450 reaction phenotyping: State of the art

Elaine Tseng, R. Scott Obach

 

Review article

The rational use of PBPK to assess the changing DDI liability in pediatrics: Model qualification and the move towards best practice

Trevor N. Johnson, Jean Dinh, Roz Southall, Amin Rostami-Hodjegan

 

[Regular Articles]

Research article

Cytochrome P450 inhibition correlates with hepatotoxicity of pesticides: Analysis using repeated-dose toxicity data in rats

Minami Shibata, Nana Uchida, Akira Ooka, Ryota Shizu, Kouichi Yoshinari

 

[Notes]

Short communication

Analysis of blood-brain barrier permeability of drugs using forensically obtained human cerebrospinal fluid and plasma in Japan

Tomoyoshi Hariba, Kenta Mizoi, Saori Takahashi, Hiroki Sunakawa, … Takuo Ogihara

 

[Commentary]

Discussion

Role of metabolites in drug-drug interactions

Nina Isoherranen


●各論文のabstractおよび論文内容詳細については,以下のリンクをご覧ください.
Drug Metabolism and Pharmacokinetics | Vol 66, February 2026 | ScienceDirect.com by Elsevier