DMPK 62に掲載予定の論文一覧 | 日本薬物動態学会

[Review]

Review article

Current status of Imaging Mass Spectrometry in drug discovery and development: A survey highlighting technical challenges and future directions

Yukari Tanaka, Hiroyuki Yokoi, Hidefumi Kaji, Yoko Urasaki, … Hiroshi Yamazaki

[Regular Articles]

Research article

Population pharmacokinetics of brexpiprazole in Japanese healthy subjects and patients with schizophrenia

Koushi Higashi, Tomohiro Sasaki, Kazuo Aoki, Daisuke Sekine, … Yosuke Kawai

Research article

Functional assessment of immortalized human brain microvascular endothelial cells with different passage numbers: A case study for a prospective proposal on variability management of in vitro blood-brain barrier models

Seiya Ohki, Mei Fukuda, Tomoyo Baba, Naomi Wakayama, … Tomomi Furihata

Research article

Exploring the effect of intracellular loop 1 genetic variants in human ABCG2 on transport activity and protein abundance

Noora Sjöstedt, Ritchie G.M. Timmermans, Marika Vieraankivi, Laura Suominen, … Heidi Kidron

Research article

Functional characteristics of equilibrative nucleoside transporter 2 (ENT2/SLC29A2) for the transport of urate as a newly identified substrate

Isamu Matake, Tomoya Yasujima, Hirotaka Matsuo, Yu Toyoda, … Hiroaki Yuasa

Research article

Converting suspension-type human primary hepatocytes to be plateable-type for use as an in vitro pharmacokinetics model

Raghda Shahin, Yoko Sakai, Kotaro Shirai, Tadahiro Hashita, … Takahiro Iwao

Research article

Drug-drug interaction between trastuzumab emtansine (T-DM1) and orally administered tacrolimus in a patient and in rats

Tomohiro Nakamura, Moeko Shimada, Makiko Takabayashi, Arimi Fujita, … Yoshimichi Sai

Research article

Investigation of pilocarpine oxidative and hydrolytic metabolism in chimeric mice with humanized liver

Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda, Hiroshi Yamazaki, Hiroshi Suemizu

Research article

Human aldo-keto reductase (AKR) 1C1 and 1C2 act as coactivators of pregnane X receptor, a master regulator of drug-metabolizing and gluconeogenesis enzymes

Rei Mitamura, Seiya Takemoto, Yuka Aoyama, Koki Morita, … Miki Nakajima

[Notes]

Short communication

Buffer compositions strongly impact the in vitro assessment of CYP fraction metabolized using human liver microsomes or expressed isoenzymes

Yuta Tamemoto, Yukihiro Shibata, Natsumi Hashimoto, Aoi Yoshitomo, … Akihiro Hisaka

Review article

In vitro liver models for toxicological research

Ichiro Fukunaga, Takanori Takebe

[Review]

Current status of Imaging Mass Spectrometry in drug discovery and development: A survey highlighting technical challenges and future directions

[Regular Articles]

Population pharmacokinetics of brexpiprazole in Japanese healthy subjects and patients with schizophrenia

Functional assessment of immortalized human brain microvascular endothelial cells with different passage numbers: A case study for a prospective proposal on variability management of in vitro blood-brain barrier models

Exploring the effect of intracellular loop 1 genetic variants in human ABCG2 on transport activity and protein abundance

Functional characteristics of equilibrative nucleoside transporter 2 (ENT2/SLC29A2) for the transport of urate as a newly identified substrate

Converting suspension-type human primary hepatocytes to be plateable-type for use as an in vitro pharmacokinetics model

Drug-drug interaction between trastuzumab emtansine (T-DM1) and orally administered tacrolimus in a patient and in rats

Investigation of pilocarpine oxidative and hydrolytic metabolism in chimeric mice with humanized liver

Human aldo-keto reductase (AKR) 1C1 and 1C2 act as coactivators of pregnane X receptor, a master regulator of drug-metabolizing and gluconeogenesis enzymes

[Notes]

Buffer compositions strongly impact the in vitro assessment of CYP fraction metabolized using human liver microsomes or expressed isoenzymes

In vitro liver models for toxicological research

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