第26回年会　ベストポスター賞受賞者とFinalist

第26回日本薬物動態学会年会のベストポスター賞は、エントリーされた93演題について選考委員による1次選考により13演題のFinalistに絞られた後、年会時にこの13演題の中から5演題がベストポスター賞に決定いたしました。
演題番号、受賞題名、報告者名、所属は以下の通りです。ベストポスター賞を受賞された皆様、おめでとうございます。

【基礎研究領域】
1-P1-02
EFFICIENT GENERATION OF MATURE HEPATOCYTES FROM HUMAN PLURIPOTENT STEM CELLS BY HNF4ALPHA TRANSDUCTION
Kazuo Takayama1), Mitsuru Inamura1), 2), Kenji Kawabata2), Kazufumi Katayama1), Katsuhisa Tashiro2), Fuminori Sakurai1）, Miho Furue-Kusuda3), Hiroyuki Mizuguchi1）,2）
1) Department of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, 2)Laboratory of Stem Cell Regulation, NIBIO, 3)JCRB Cell Bank, NIBIO

1-P1-04
NUCLEAR RECEPTOR CAR DOWN-REGULATES HEPATIC PPARalpha;-MEDIATED EXPRESSION OF HMGCS2, A KEY ENZYME OF KETOGENESIS, IN MICE AND HUMANS
Yuta Otsuka, Kouichi Yoshinari, Yasushi Yamazoe
Graduate School of Pahermaceutical Sciences, Tohoku University

【臨床研究領域】
1-P1-08
GENETIC AND EPIGENETIC REGULATION OF GAMMA-GLUTAMYL HYDROLASE ACTIVITY IN JAPANESE HEALTHY VOLUNTEERS
Takayuki Suyama, Yukari Hara, Tomomi Hosogai, Nobuhiro Nishimura, Kohji Naora
Department of Pharmacy, Shimane University Hospital

【創薬研究・開発領域】
1-P1-11
UTILITY OF MALDI IMAGING MASS SPECTROMETRY IN DRUG DISCOVERY: HISTOLOGICAL DISTRIBUTION OF CHLOROQUINE AND ITS METABOLITE(S) IN THE OCULAR TISSUE OF PIGMENTED RATS
Hidefumi Kaji1), Yasuhiro Yamada1), Henry Shion2）, Motoji Oshikata 3), Yukari Haramaki 3)
1) DMPK Research Laboratory, Mitsubishi Tanabe Pharma Corporation, 2)Waters Corporation，
3)Nihon Waters

1-P1-13
THE QUANTITATIVE PREDICTION OF CLEARANCE IN HUMAN USING CYP3A4 TRANSGENIC MICE
Tetsuya Mitsui1), Takayuki Nemoto1), Taiji Miyake1), Shunsuke Nagao1), Kotaro Ogawa1), Motohiro Kato1), C. Roland Wolf2）, Nico Scheer3), Masaki Ishigai1)
1) Pre-clinical research dept. research division, Chugai Pharmaceutical Co.,Ltd., 2)CXR Biosciences Ltd.,
3)TaconicArtemis GmbH

なお、Finalist 13演題のうち8演題については、下記の通りです。

1-P1-01
PLACENTAL GENE EXPRESSION RESPONSES TO MATERNAL CALORIC RESTRICTION IN THE RAT
Masatoshi Tomi1) , Machiko Sekiguchi1), Tomohiro Nishimura1), Ichiro Takasaki2), Emi Nakashima1)
1) Faculty of Pharmacy, Keio University, 2)Life Science Research Center, University of Toyama

1-P1-03
AHR PATHWAY MEDIATES AN ANGIOGENIC FACTOR, VEGF EXPRESSION UNDER LOW GLUCOSE CONDITIONS IN HEPG2.
Jun Terashima, Wataru Habano, Toshie Gamou, Shogo Ozawa
Pharmacodynamics and Molecular Genetics Lab, School of pharmacy, Iwate Medical University

1-P1-05
DEVELOPMENT OF A NOVEL CLAUDIN BINDER AND ITS APPLICATION INTO MUCOSAL ABSORPTION
Azusa Takahashi, Yumiko Saito, Yohei Kakamu, Akihiro Watari, Masuo Kondoh, Kiyohito Yagi
Laboratory of Bio-Functional Molecular Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University

1-P1-06
SEX-DEPENDENT DIFFERENCES OF CYP3A EXPRESSION IN CYP3A-HAC MICE
Mika Endo1) , Mio Watanabe1) , Kaoru Kobayashi1), Yasuhiro Kazuki2）, Yuki Yamazaki1), Shoko Takehara2）, 3), Mitsuo Oshimura2）, Kan Chiba1)
1) Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, 2)Graduate School of Medical Science, Tottori University, 3)Chromocenter Inc.

1-P1-07
ABCC2 GENOTYPE IS ASSOCIATED WITH EFFICACY OF FIRST-LINE FOLFIRI IN JAPANESE PATIENTS WITH ADVANCED COLORECTAL CANCER
Yuko Akiyama, Ken-Ichi Fujita, Hiroo Ishida, Yu Sunakawa, Keishi Yamashita, Kaori Kawara, Keisuke Miwa, Shigehira Saji, Yasutsuna Sasaki
Department of Medical Oncology, International Medical Center, Saitama Medical University

1-P1-09
THE USEFULNESS OF CYP3A4/OATP1B1-DOUBLE EXPRESSING CELLS FOR EVALUATION OF HUMAN PHARMACOKINETICS
Miki Fujishima1), Shinsuke Aoyama1), Yasuhisa Adachi1), Shinichi Ninomiya1), Koichi Yoshinari2）, Yasushi Yamazoe2）, Momoko Sunouchi3), Kenichi Nakazawa3), Seiichi Ishida3)
1) ADME & Tox. Research Institute, Sekisui Medical Co., Ltd, 2)Graduate School of Pharmaceutical Sciences, Tohoku University, 3)National Institute of Health Sciences

1-P1-10
ROLE OF GENOMIC DNA METHYLATION DURING THE HEPATIC MATURATION OF HepaRG HUMAN HEPATOCYTE BIPOTENT PROGENITORS
Takashi Kubo1), Tamaki Hori1), Atsuko Miyajima2）, Yukie Kuroda1), Momoko Sunouchi1), Anne Corle3), Fabrice Morel 3), Shogo Ozawa4), Yuko Sekino1), Seiichi Ishida1)
1)Division of Pharmacology, National Institute of Health Science 2)Division of Medical Devices, National Institute of Health Sciences, 3)INSERM UMR 991, Hopital Pontchaillou, University of Rennes, 4)Department of Pharmacodynamics and Molecular Genetics, School of Pharmacy, Iwate Medical University

1-P1-12
ULTRAFAST SPE INTEGRATED WITH TOF-MS INCREASES THE THROUGHPUT OF METABOLIC STABILITY ASSAYS AND ENABLES ANALYSIS OF METABOLITES
Miller Vaughn1), Michelle Romm1) , Nikunj Parikh1), Yuqin Dai2）, William Lamarr1), Masahiro Maeda3), Keith Waddell2）, Can Ozbal1), 2）
1) Agilent Technologies, 2)Agilent Technologies, 3)Tokyo Medical and Dental Universitiy

以上