|
Effects
of Single and Repeated Treatment with Itraconazole on the Pharmacokinetics
of Midazolam in Rats
Yasufumi SAWADA, Sayuri TAKEDOMI, Hirotami
MATSUO, Katsuhiro YAMANO, Tatsuji IGA and Hisakazu OHTANI |
275 |
|
Evaluation
of Gastrointestinal Transit Characteristics of Oral Patch Preparation
Using Caffeine as a Model Drug in Human Volunteers
Sudarat
EAIMTRAKARN, Y. V. Rama PRASAD, Shivanand P. PUTHLI, Yukako YOSHIKAWA,
Nobuhito SHIBATA and Kanji TAKADA |
284 |
|
Nonlinear
Pharmacokinetics of Aprindine in Guinea Pigs
Mikiko SHIMIZU,
Toshikuni OHOTA, Mutumi KISHIDA and Hiroyasu OGATA |
292 |
|
Characterization
of Ligand Binding Sites on the α1-Acid Glycoprotein in Humans,
Bovines and Dogs
Kazuaki MATSUMOTO, Katsuaki SUKIMOTO, Koji
NISHI, Toru MARUYAMA, Ayaka SUENAGA and Masaki OTAGIRI |
300 |
|
Analysis
and Prediction of Absorption Behavior for Theophylline Orally Administered
as Powders Based on Gastrointestinal-transit-Absorption (Gita)
Model
Keitaro KADONO, Jun-ichi YOKOE, Ken-ichi OGAWARA,
Kazutaka HIGAKI and Toshikiro KIMURA |
307 |
|
Strategy
for Structure Elucidation of Drug Metabolites Derived from Protonated
Molecules and (MS)n Fragmentation of Zotepine, Tiaramide and
their Metabolites
Zenzaburo TOZUKA, Hayato KANEKO, Toshifumi
SHIRAGA, Yasuyuki MITANI, Akio KAWAMURA, Akira KAGAYAMA and Anri
AOBA |
316 |
|
Metallokinetic
Study of Zinc in the Blood of Normal Rats Given Insulinomimetic Zinc(II)
Complexes and Improvement of Diabetes Mellitus in Type 2 Diabetic GK Rats
by their Oral Administration
Jun FUGONO, Keisuke FUJIMOTO,
Hiroyuki YASUI, Kenji KAWABE, Yutaka YOSHIKAWA, Yoshitane KOJIMA and
Hiromu SAKURAI |
340 |
|
Molecular
Characterization of Two Monkey Dihydrodiol Dehydrogenases
Yu
HIGAKI, Takeshi KAMIYA, Noriyuki USAMI, Syunichi SHINTANI, Hiroaki
SHIRAISHI, Shuhei ISHIKURA, Ikuo YAMAMOTO and Akira HARA |
348 |