|
The
Potential for an Interaction between MRP2 (ABCC2) and Various Therapeutic
Agents: Probenecid as a Candidate Inhibitor of the Biliary Excretion of
Irinotecan Metabolites
M. HORIKAWA, Y. KATO, C. A. TYSON and Y.
SUGIYAMA |
23 |
|
Evaluation
of Blood-Brain Barrier Transporters by Co-culture of Brain Capillary
Endothelial Cells with Astrocytes
Y. KIDO, I. TAMAI, T.
NAKANISHI, T. KAGAMI, I. HIROSAWA, Y. SAI and A. TSUJI |
34 |
|
Selective
Suppressions of Human CYP3A Forms, CYP3A5 and CYP3A7, by Troglitazone in
HepG2 Cells
M. OGINO, K. NAGATA and Y. YAMAZOE |
42 |
|
Activities
of Cytochrome P450 Enzymes in Liver and Kidney Microsomes from Systemic
Carnitine Deficiency Mice with a Gene Mutation of Carnitine/Organic Cation
Transporter
H. YAMAZAKI, H. IKETAKI, A. SHIBATA, M. NAKAJIMA
and T. YOKOI |
47 |
|
Induction
of Cytochrome P450 1A1 in Mice by Repeated Oral Administration of
Propranolol
S. NARIMATSU, M. MOCHIDA, K. UENO, T. HORIE, S.
YAMAMOTO and T. SUZUKI |
54 |
|
Studies
on the Metabolic Fate of M17055, a Novel Diuretic (4): Species Difference
in Metabolic Pathway and Identification of Human CYP Isoform Responsible
for the Metabolism of M17055
H. NAKAJIMA, T. NAKANISHI, K.
NAKAI, S. MATSUMOTO, K. IDA, T. OGIHARA and N. OHZAWA |
60 |
|
Comparative
Analysis of In Vitro and In Vivo Pharmacokinetic Parameters Related to
Individual Variability of GTS-21 in Canine
R. AZUMA, M. KOMURO,
Y. KAWAGUCHI, K. OKUDAIRA, M. HAYASHI and H. KIWADA |
75 |
|
Clarification
of the Mechanism of Structural Change Induced by Reoxygenation following
the Induction of Lipid Peroxidation in Caco-2 Cell
Monolayers
M. TOMITA, M. NAGIRA, M. HAGA and M. HAYASHI |
83 |